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Inductively Coupled Plasma Mass Spectrometer (ICP-MS)

Inductively Coupled Plasma Optical Emission Spectrometer (ICP‑OES) and Inductively Coupled Plasma Mass Spectrometer (ICP‑MS)—both state-of-the-art instruments from Thermo Fisher Scientific—are capable of performing multi‑element trace analysis of heavy metals. These instruments are primarily used to analyze arsenic, cadmium, mercury, lead, nickel, antimony, and other heavy metals in the company’s raw materials and finished products.

Gas Chromatography-Mass Spectrometry Laboratory

The high-end model developed and marketed by Thermo Fisher Scientific in the United States builds upon a gas chromatograph and is equipped with an attached mass spectrometer. This instrument is primarily used to detect the presence of the hazardous substance 1,4-dioxane and to quantify its levels in cosmetic products, as well as to analyze the content of raw materials.

High-Performance Liquid Chromatography Detector (HPLC)

The high-performance liquid chromatography system from Thermo Fisher Scientific, equipped with ultraviolet (UV) and diode-array (DAD) detectors, is capable of performing both qualitative and quantitative analyses for most compounds. Currently, this instrument is primarily used to detect and quantify preservatives and potentially hazardous substances in cosmetics, such as phenoxyethanol, chlorphenesin, phenol, and propylparaben.

Anticorrosion Challenge – Biosafety Cabinet

The government‑registered Biosafety Level 2 laboratory is primarily used for the isolation and identification of pathogenic microorganisms, as well as for conducting antimicrobial challenge tests on products. It is equipped with three biosafety cabinets and a ultra‑low temperature freezer. Currently, it maintains more than a dozen standard strains— including Staphylococcus aureus, Candida albicans, Escherichia coli, and Pseudomonas aeruginosa—obtained from national strain preservation institutions, which are mainly employed for method development and routine monitoring activities.

Microbial culture

The incubation room is equipped with 15 incubators, each of which undergoes annual external calibration to ensure compliance with all temperature requirements for point‑by‑point coverage testing. In addition, the room is fitted with external thermometers to verify and monitor the daily temperatures of the incubators.

Ultra-clean sterile room

Microbiological Testing—Equipped with three laminar flow hoods, two electronic balances, a stomacher homogenizer, and other instruments, this facility is primarily used for monitoring the total viable count in raw materials and finished products, as well as for pre‑enrichment processing prior to the detection of molds, yeasts, and pathogenic bacteria.

Infrared Spectroscopy Laboratory

The infrared spectrometer is manufactured by Thermo Fisher Scientific of the United States and is equipped with an ATR accessory. It is lightweight and portable, primarily used for rapid qualitative analysis of raw materials, enabling users to minimize effort and investment while mitigating product‑quality risks associated with these materials. The FEI scanning electron microscope is employed for product development and routine quality‑control analysis and investigation.

Specialized Production 2

Lyophilizers and Blow-Fill-Seal (BFS) automated filling machines Adhering to the principle of brand confidentiality, Zhenchen operates a secure production facility and is the only company nationwide equipped with both low-temperature dehydration technology and a BFS system, with a daily output capacity of 30,000 to 50,000 units. To date, Zhenchen has shipped over 10 million units, achieving an impeccable record of zero data breaches.

Specialized Production 3

A robust production capacity system Formulation Workshop: Boasts three major formulation workshops—powder, wax-based, and comprehensive—equipped with over 100 pieces of machinery, including vacuum emulsification kettles, vacuum defoaming and molten-material systems, ultra‑fine air mills, high‑speed powder‑mixing homogenizers, and high‑speed dispersion systems. Production System: Comprises five major production lines—skincare manufacturing, wax‑based filling, powder canning, low‑temperature dehydration with 3D precision carving, and BFS—supported by more than 400 pieces of production equipment. Packaging Workshop: Features a total of 50 packaging assembly lines, including 15 for powders and 35 for creams, with over 200 packaging machines in operation.

Specialized Production 4

Negative-pressure weighing hood and weighing system Weighing area: Independently designed with primary, secondary, and high-efficiency laminar airflow to ensure that the weighing environment is free from external contamination and cross-contamination risks. Weighing system management: The host computer downloads the formulation weighing list, and material identification via barcode scanning enables material traceability and first-in-first-out management, ensuring precise weighing while effectively minimizing operator errors.

Specialized Production 5

Ventilation System and Compressed Air System Robust and stable utility systems: Ensure that the production environment—specifically, the workshop—is fully automated and monitored via a host computer, with real-time tracking of temperature, humidity, and air pressure in each production area, along with scheduled disinfection and fresh-air ventilation. Clean Compressed Air System: The system is designed around the world’s most advanced dry‑type oil‑free air compressor, effectively preventing oil contamination from the equipment. It incorporates multi‑stage precision filters, an air dryer, a desiccant adsorption dryer, and a sterilizing filter, guaranteeing that the compressed air used in production has an oil content of ≤0.01 mg/m³ and a water‑vapor dew point of ≤−20°C, bringing it close to pharmaceutical‑grade compressed air standards.

Specialized Production 6

Purified Water System Water quality far exceeds pharmacopoeial standards, with a total microbial count of less than 1 CFU/mL. This is an unattended, fully automated system featuring intelligent configuration. Designed, manufactured, commissioned, and validated in accordance with FDA requirements. Equipped with an S7‑1500 control system that complies with GAMP 5 guidelines and FDA 21 CFR Part 211 regulations, and includes audit trail functionality. Key components are sourced from leading international brands, including Gemu/Burkert, Wika, Jumo, M+T, and others.

Specialized Production 7

EKATO Emulsification Kettle Imported from Germany, the EKATO emulsification kettle is one of the highest‑quality and most stable emulsification and formulation equipment available worldwide. It complies with GMP requirements and features integrated CIP and SIP capabilities. The homogenizer delivers a maximum peripheral speed of 27 m/s and a shear rate of up to 54,000 s⁻¹. Equipped with a pre‑mixing unit, it supports both internal and external circulation homogenization, making it ideal for producing ointments, gels, suspensions, creams, toothpastes, cosmetics, skin‑care products, and other formulations across low, medium, and high viscosity ranges.

Specialized production 8

BFS blow-fill-seal integrated machine and nitrogen generator By leveraging pharmaceutical equipment and processes to manufacture cosmetic products, we can minimize contamination during production and ensure product freshness during storage. Blow-fill-seal technology enables the seamless execution of blow molding, filling, and sealing within a single piece of equipment, with all operations performed under sterile conditions. Validation has demonstrated that the equipment’s contamination rate can be kept below 0.1%. Furthermore, based on a comprehensive analysis of media‑filling data, the BFS system achieves an even lower contamination rate of just 0.001%. This process is equipped with nitrogen‑purge filling, using nitrogen of ≥99.999% purity, which not only ensures aseptic filling but also provides nitrogen‑based protection for oxidation‑sensitive formulations.

Specialized production 9

Automatic powder compaction machine Combining robotics, vision systems, mechanical modules, and programmable process control, this system enables fully automated production of pressed powders, blushes, eyeshadows, and other powdered cosmetics. It minimizes human involvement and intervention, delivering cost-effective, high‑quality manufacturing to customers.

Specialized production 10

Fully Automatic Lipstick Filling Machine A range of fully automatic lipstick filling machines capable of producing solid‑state products in single‑color, multi‑color, and embossed designs. While offering customers diverse production processes, these machines also deliver cost‑effective solutions with stringent quality control.

Scanning electron microscope

Materials science research conducted using a scanning electron microscope can be applied to the development of novel micron-scale materials, primarily for the design and investigation of new powdered products.

MPA Multifunctional Testing Platform

The MPA system is a multifunctional analytical platform that can simultaneously interface with multiple probes, each offering a distinct analytical window.

Tewameter® TM Nano Ultra-Compact Transcutaneous Water Loss Meter

The ultra‑small probe (with a diameter of only 2 mm) can accurately and rapidly measure TEWL, expressed in g/h/m² (under pressure, with biting, and at different temperatures). The Tewameter® TM Nano is ideally suited for measuring small body areas, such as nails, lips, hairy scalp, hair, or small animals.

VC 20 Skin Analysis System (Visioscan® VC 20plus)

The Visioscan® VC 20plus is a unique UVA‑light camera with high resolution, enabling direct examination of the skin surface and facilitating the evaluation of product exfoliation efficacy (assessing cleansing performance), as well as changes in wrinkles, skin roughness, and smoothness, and analyzing skin surface morphology.

Antera 3D Imaging System (3D Imaging System)

Antera 3D measurement is highly accurate across all measurement parameters. Tests conducted under controlled conditions on the morphological analysis of artificial skin samples—examining wrinkles, texture, volume, and more—demonstrate a measurement error of less than 2%. Multi-channel analysis: it can simultaneously display initial and follow-up images of color, wrinkles, texture, pigmentation, erythema, and other features.

Cosmetic SPF Sun Protection Factor Analyzer UV-2000S

The UV-2000S Sun Protection Factor Analyzer employs cutting-edge optical and electronic components, along with advanced software technologies, integrated into a proven industry-standard system architecture to determine in vitro SPF and UVA protection factors, thereby enabling accurate labeling of sun protection products during the development process.

Skin pH Test Probe LAQUA PH220

The semiconductor pen‑type pH meter is a simple, portable device that measures skin pH using a solid‑state ISFET. Before measurement, it undergoes calibration and adjustment; then, by gently touching the skin surface with the handheld probe, the measured skin pH value is displayed on the screen.

Portable Skin Elasticity Tester Delfin Elastimeter

When the probe makes contact with the skin to begin testing, it is immediately pressed against the skin surface. Once the base plate is fully in contact with the skin, the indenter undergoes a constant deformation, similar to that of a spring. As the skin resists this deformation, the instantaneous skin elasticity (ISE) can be measured.